Worcester centre Ben Te’o has been dominated out of the England tour of South Africa with an harm to a quad muscle in his leg.
Te’o, 31, requires surgical procedure on what’s being described as a “minor” situation.
Gloucester full-back Jason Woodward, Northampton centre Piers Francis and Wasps quantity eight Nathan Hughes have been referred to as into the 34 man squad.
They change Te’o, and the opposite injured gamers Cameron Redpath and Jack Willis, in Eddie Jones’ squad.
England’s tour of South Africa, which options three Exams, begins on 9 June at Ellis Park in Johannesburg.
Jones’ facet have misplaced 4 matches in a row – together with Sunday’s non-cap match in opposition to the Barbarians – and final received on 10 February in opposition to Wales within the Six Nations.
Te’o has performed 13 occasions for England and final featured in opposition to Eire at Twickenham in March.
The previous rugby league participant solely appeared 12 occasions for Worcester final season and travelled to Australia during the campaign to undergo a self-funded rehabilitation programme after having a plate inserted in his ankle.
Radio 5 stay rugby reporter Chris Jones
Te’o turns into the latest England player to leave camp injured, though the RFU says the centre has aggravated an present harm and now wants “minor restore” to his quad.
Both method, it means England may have a new-look midfield at Ellis Park, with one other stalwart Jonathan Joseph additionally lacking.
Alex Lozowski – a category act at Saracens this season – now has an exquisite likelihood of sporting that quantity 13 shirt come the primary Take a look at with the Springboks, whereas Henry Slade can also be a contender.